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Ghrelin and sleep and heat regulation

I have been noticing in several posts that people report feeling colder after this surgery. Some people attribute it to the weight loss, but others say they have lost large amounts of weight before and not had this effect. I decided to do some research. There are several articles that say increasing ghrelin increases body temperature. This article suggests that rats that don't produce ghrelin have trouble regulating body temperature in cold environments. They also have less nonREM sleep, (more dream time, less deep restful sleep), but they stay awake better during the day. I guess what is interesting to me is this hormone is a big player in sleep and thermo-regulation. I was wondering what others have personally noticed about their changes in sleep and ability to adjust to cold or hot temperatures.

Personally. I have noticed I sleep less, 6-7 hours at night. I feel awake but tire easily (which I think is more related to surgery recovery). I have definitely felt colder and always have a blanket over me.

http://www.pnas.org/content/early/2009/08/03/0903090106.full.pdf

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  • currysusan123
    currysusan123

    I have lost 84 lbs so far. At 281 I still have 130 lbs to lose. I have been REALLY been having problems keeping warm. I knew this would be an issue when I was thin, but I still have a lot of weight

  • ouroborous
    ouroborous

    Not terribly concerned if the only significant side effect is a perception of being cold. I'll stack that up against diabetes & heart disease any day. Metabolism is complex, so I wouldn't at al

  • Another reason I can't wait to be sleeved!! It is not a femine feeling to sweat like you have done an hour of high impact aerobics and all you have done is walked one corridor of the mall!!

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Thank you! I wonder why they didn't report the ghrelin levels at 5 year post op since they followed up the patients up to that point? Maybe it is in the main body of the article.

I read an article (I can't find anymore) that said that ghrelin levels are reduced after a person eats and that in obese patients, ghrelin levels were very low (I guess for those who snack a lot?). I wish I could find it!

Thank you! I wonder why they didn't report the ghrelin levels at 5 year post op since they followed up the patients up to that point? Maybe it is in the main body of the article.

I read an article (I can't find anymore) that said that ghrelin levels are reduced after a person eats and that in obese patients, ghrelin levels were very low (I guess for those who snack a lot?). I wish I could find it!

A total of eight patients (30.8%) were at chronic need for proton pump inhibitor medication due to severe reflux. Plasma ghrelin levels were reduced from 593 +/- 52 to 219 +/- 23 pg/ml 12 months postoperatively, with a slightly, non-significant increase toward the 5-years values of mean 257 +/- 23 pg/ml.

CONCLUSIONS:

At 5-year follow-up, a mean EWL of 55.0 +/- 6.8% was achieved, indicating that SG leads to stable weight loss. Beside significant weight regain, severe reflux might necessitate conversion to gastric bypass or duodenal switch. After an immediate reduction postoperatively, plasma ghrelin levels remained low for the first 5 years postoperatively.

  • 3 weeks later...

I sure will. My appt is in a couple weeks. I'm going to friend you so in case I forget where this thread is I can get back to you. :-)

Hi former_vbg, what did your neurologist say?

Well, I had bloodwork done at 3 and 6 months, and nothing came up showing a problem- but I don't know that he specifically checked for that. What do they have to request when checking?

A FULL thyroid panel. Not just TSH, but free T3 and free T4 as well. Most docs do not check these as a standard.

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