I was just wondering what people's experiences were with weight loss surgery while being on an atypical antipsychotic. I have bipolar 1, and I'm on Seroquel and Abilify. I know the Seroquel contributes to my weight, but whenever we've tried to get me off of it, things have always worsened. Did you lose weight more slowly? Did you have to go off the medication? I'm especially curious if you've had gastric bypass surgery.

I'm on Rexulti for depression along with a few other things. It is an atypical antipsychotic. I haven't had surgery yet so I can't say how it affects weight loss but my psych feels it is pretty weight neutral so shouldn't be a problem. She said most of her patients lose the weight on their meds, it just takes a bit sometimes. I'm guessing some meds can slow the process if you know they are contributing to your weight already, it just depends on the individual, as with most things.

My psych didn't seem concerned about any of my meds after surgery. Just that I took them. He had to switch my wellbutrin to immediate release but that was the only change he made to my medications. My mood stabilizer is supposed to be taken with food to be absorbed properly and I don't manage that very well and it's apparent. 2.5 weeks out from my surgery and my husband is already ready to divorce me because of my mood fluctuations and grumpusness.