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Early results show weight loss may reduce osteoarthritis and osteophytes
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A recent study was conducted by Dr. Jos Runhaar of the Erasmus MC, Department of General Practice, Rotterdam, the Netherlands, and colleagues.
These researchers examined the records of 353 overweight or obese women (BMI ≥ 27 m/kg2), a subset of participants in the PROOF study (Prevention of Knee Osteoarthritis in Overweight Females), which was designed to examine the preventive efficacy of diet and exercise and glucosamine sulphate supplementation on the incidence of knee osteoarthritis. On average, the participants in this subgoup were 56 years old, and had BMIs of 33 kgm/m2. They compared the arthritis incidence in women who met a goal of losing either 5 kgm (about 11 pounds) or 5 percent of their body weight within 30 months of beginning the study, to the incidence in women who did not meet that goal. Initially, the women did not suffer from osteoarthritis, as determined by X-ray evidence of joint space narrowing.