Sleeved 6/27, and have been taking Omeprazole (Prilosec) once daily since surgery, doctor told me to take it for 30 days after surgery. My 30th day is coming up and I'm just wondering if anyone else has had any noticeable change in stomach behavior after not taking the antacid medication any longer.

I was told to try to wean off it - and sometimes I had a sour stomach for about 3 months, I would take it and then when I felt that way but haven't needed it at all for about 6 weeks.

Yes, PPIs like omeprazole need to be stepped off of on their dosing, or else rebound reflux or heartburn can occur. Try cutting the dose in half for a week or two, or alternate doses with an H2 inhibitor like Zantac or Pepcid.