Flora of Gut - can changing your gut bacteria bring weight loss?

[utahgirll 81]

Latest on this!

http://www.bariatricnews.net/?q=news/111566/preloaded-nutrients-could-mimic-bypass-surgery

Here's the study:

http://gut.bmj.com/content/early/2014/07/11/gutjnl-2014-306834.full?sid=ad60c3be-d4d6-4fc4-94eb-ae323d9bc3cb

CONCLUSION of study in UK

We conclude that the distal gut of humans and mice is extensively equipped with sensors for products of fat and Protein digestion, and that these associate with specific signalling pathways, two of which have been shown here. These are in turn associated with the release of specific mediators. We have uncovered a role for 5-HT in the response to luminal aromatic AAs, which may contribute to metabolic and behavioural responses to exposure of the distal gut to a meal. It is already known that oral nutrient preloads reduce subsequent food intake15 and that bypass surgery reduces food intake by shunting nutrient to the distal gut. By refining nutrient preloads and formulating them to target the distal gut, we expect to develop a successful weight loss and antidiabetic strategy prior to and possibly in place of bypass surgery.

Lean folks have different gut flora (bacteria) than obese folks. Researchers have been working with mice on transplanting lean flora. How does the lean bacteria work?

Some researchers say this is what is happening with human weight loss surgery... the actual change or rearrangement in the gut bacteria, from the surgery, is the reason for the weight loss after a bypass/ or does the flora change for some other reason?

http://www.sciencemag.org/content/341/6144/351.summary

http://stm.sciencemag.org/content/5/178/178ra41.abstract

Interesting. Wouldn't it be great to get a transplant of the lean bacteria without the bypass? This is one thing the researchers are looking at. A transplant of lean flora from a bypassed patient or a lean person to an obese person that has not had any surgery.

Here are some articles for your perusal. Although this isn't actually something that is a procedure... at least now, could it be? How about fecal transplantation? Researchers are talking about this, also want to find exactly which bacteria is the "lean" one, and use this only. It has the ew factor, getting beyond it, why not. Fecal transplant has successfully cured (90% rate) c-diff. Then again, just consuming non-inflammatory type foods that are good for the gut, is discussed too.

http://www.nytimes.com/2013/03/28/health/studies-focus-on-gut-bacteria-in-weight-loss.html

http://www.huffingtonpost.com/2013/09/05/gut-bacteria-obesity-spur-protect_n_3875034.html

http://www.nytimes.com/2013/09/06/health/gut-bacteria-from-thin-humans-can-slim-mice-down.html?_r=1&

http://www.sciencemag.org/content/341/6150/1241214

http://chriskresser.com/a-healthy-gut-is-the-hidden-key-to-weight-loss

http://www.naturalnews.com/036331_gut_flora_weight_loss_body_fat.html

Edited July 15, 2014 by utahgirll