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I was still having considerable heartburn/acid, even though I was taking Prilosec 2x day and Zantac in the evening. I had already tried Prevacid 2x day and Prilosec worked better but I still had the issue.
Nurse Practitioner gave me Nexium -- she said it is considered the strongest PPI. I'm taking it once a day ( if I need to go to 2x a day I can).
IT WORKED! I have not have any heartburn( other than in the morning before I take my Nexium!)
What a difference not to have the nagging heartburn......