I’m about 2.75 years out and I’ve been taking a PPI to treat Gerd daily. Has anyone taken Omeprazole long term or any PPI. I’m concerned with some of the literature I see. It links PPIs like Omeprazole to esophagus cancer. I’m confused does PPIs help or hurt the cancer risk. I know there are other problems associated. Anyone with gerd post op I’m interested to hear your thoughts!!

The information on PPI doesn't seem to be really clear at the moment. There seems to be evidence that the longterm use of PPI is problematic when it comes to renal failure and to osteoporosis as well. The recommendations are starting to go against the long term use of PPI and back to H2-blockers.

I personally am glad that I seem to be finally able to not needing them. Haven't taken them since a few days and it feels ok so far. However, it took a long weaning period and I'm still not convinced that I won't be needing them in the future. Gotta wait for the next EGD in autumn to know for sure I guess.

Talk to your surgeon and/or PCP if they see a way to wean the PPI. How much are you taking of them right now?

I've discussed this at length with my team and when extreme GERD is not well controlled with PPIs they try other paths erring on the side of caution concerning the new info on PPIs.

You should check in with your physician

Apparently when i was moved up to the highest dose/highest frequency they didnt want that to continue indefinitely. They prefer to opt for revisions to solve the problem completely before other complications start.

Edited June 9, 20197 yr by GreenTealael

I took it for at least 5 years prior to sleeve surgery. Now I don't need it anymore.

5 minutes ago, GreenTealael said:

Apparently when i was moved up to the highest dose/highest frequency they didnt want that to continue indefinitely. They prefer to opt for revisions to solve the problem completely before other complications start.

The risk regarding the above mentioned issues seems to be higher dependent on how often you have to take the PPI, e. g. taking two pills a day seems to be associated with higher risk. Take care!

it wouldn't be a risk for esophageal cancer - untreated GERD is what can cause that - but they think it CAN be risk for things like renal issues, as someone else mentioned. And a few other things as well (I think I remember reading that there may be some risk for dementia, too - but I can't remember. At any rate, several things). They're still researching this, but right now the thought is that short-term use is OK, but not long-term. Those days of putting people on them for years & years are over...

Man I haven’t been to active the last year on this forum/app/website. I let myself down this community is awesome! We work together and educate! You guys calmed me down but I’ll still be getting in with a primary care this week!

Man I haven’t been to active the last year on this forum/app/website. I let myself down this community is awesome! We work together and educate! You guys calmed me down but I’ll still be getting in with a primary care this week!

Make sure you take care of your health. Check with your doctors and read medical journals.