Jump to content
×
Are you looking for the BariatricPal Store? Go now!

Fat Tissue Growth In Rodent Models Suppressed By Turmeric Extract



Recommended Posts

food, indicating curcumin did not affect appetite, but mice fed the curcumin supplemented diet did not gain as much weight as mice that were not fed curcumin.

"Curcumin appeared to be responsible for total lower body fat in the group that received supplementation," said Meydani, who is also a professor at the Friedman School of Nutrition Science and Policy at Tufts. "In those mice, we observed a suppression of microvessel density in fat tissue, a sign of less blood vessel growth and thus less expansion of fat. We also found lower blood cholesterol levels and fat in the liver of those mice. In general, angiogenesis and an accumulation of lipids in fat cells contribute to fat tissue growth."

Writing in the May 2009 issue of the Journal of Nutrition, the authors note similar results in cell cultures. Additionally, curcumin appeared to interfere with expression of two genes, which contributed to angiogenesis progression in both cell and rodent models.

"Again, based on this data, we have no way of telling whether curcumin could prevent fat tissue growth in humans." Meydani said. "The mechanism or mechanisms by which curcumin appears to affect fat tissue must be investigated in a randomized, clinical trial involving humans."

This study was funded by a grant from the United States Department of Agriculture. Asma Ejaz, a graduate student who worked on this project received a scholarship grant from the Higher Education Commission of Pakistan.

Ejaz A, Wu, D, Kwan P, and Meydani M. Journal of Nutrition. May 2009; 139 (5): 1042-1048. "Curcumin Inhibits Adipogenesis in 3T3-L1 Adipocytes and Angiogenesis and Obesity in C57/BL Mice. 919-925."

Source:

Andrea Grossman

Tufts University, Health Sciences

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
Sign in to follow this  

  • Recent Topics

  • Most popular:

  • Recent Status Updates

    • *Meaghan*

      I met with my surgeon on Friday.. I've completed all my tests and all my nutrition meetings as well as meeting the weight loss requirements for my insurance. We are officially submitting to insurance for approval and I was given a surgery date of January 16th 2020 (13 days before my birthday!) Fingers crossed all goes through 
      · 0 replies
      1. This update has no replies.
    • Krestel

      Ok, now im getting old...my body gets me up at my normal 5am dog walk even when it's the weekend, vacation, and most importantly when I'm sick. So now that I have more energy, my body wants to make sure I suffer even longer during the day when I have a cold! Damn being healthy again! (:D)
      · 1 reply
      1. UphoseDep

        http://dev.x3dt.info/forum/profile.php?id=18137 ai us palm

    • GreenTealael

      At my Primary Physician appt, the Doc said you know you lost a whole person. When you started seeing me you were 265lbs now you're 148lbs.
      She's right... I lost the fun me 😂 Joking Joking Joking. It's amazing who keeps track when you don't like insurance and browsers feeds
      · 2 replies
      1. Orchids&Dragons

        I think you're fun! You must have been a firecracker before!

      2. GreenTealael

        I don't even drink anymore 😂

    • Krestel

      First head cold since the surgery....at least I know that my body is back to "normal". /sigh
      · 0 replies
      1. This update has no replies.
    • SabrinaGoddess

      Dietitian scheduled 11/18
      Mental Evaluation scheduled 11/18
      OMG we moving forward
      All things working toward my Dec 9th surgery date!

      · 0 replies
      1. This update has no replies.
  • Trending Topics

  • Together, we have lost...
      lbs
    ×