BG, The first time I started Effexor I lost a lot of weight, (25 lbs) without trying. I just wasn't interested in food. That was years ago when it first came out.Then for whatever reasons I went off it. Then I went back on it and have had good results. I didn't loose a lot of weight because they change the med. to time release. It delivers the medicine slower and longer. I also had a full hysterectomy in 2006. I take perarin 0.45 mg. Its second to the lowest dose according to my dr. The lowest dose I was still having the unbearable hot flashes. I went on this dose and zero hot flashes. I am grateful not to have them. I would love to on on the Bio-iden. but for the same reason, I hear they can be quit costly. I haven't ruled them out, I just am so content with the dose of Premarin I don't want to mess with anything.....
One last comment BG, one word of warning I know from Effexor is when the time comes when you want to go off of them, they have a not so fun withdrawal, "serotonin syndrome zap" thats what I call it.....its describes as brain zaps, feels like vertigo. But it does pass. You just taper off slowly. Anyway, its been a good medicine for me. Take care.