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Showing content with the highest reputation on 03/03/2017 in Posts

  1. 2 points
    According to the internet: Adipose tissue, or fat, is an anatomical term for loose connective tissue composed of adipocytes. Its main role is to store energy in the form of fat, although it also cushions and insulates the body. Excess adipose tissue (fat cells) can lead to problematic changes in metabolism, blood sugar control and blood pressure. Recently scientist have been exploring the role of fat cells acts on the brain to signal satiety (hunger control). More recently, researchers have been delving into the mechanisms that adipose tissue uses to affect other parts of the body. A recent report in the journal Nature investigates one possible source of such control. To describe the study we have to define a couple of terms: microRNA (miRNA): small (19-22 nucleotides long) segments of RNA that do not code for Proteins. There are many different types of miRNAs in the circulation and in different tissues, and they have various functions in the body. In general, they act to prevent translation of mRNAs and thus decrease the production of the corresponding proteins. Dicer: an enzyme found in adipose as well as other tissues that processes miRNAs — without it miRNAs aren't produced. Led by Dr. C. Ronald Kahn of the Joslin Diabetes Center of Harvard University, researchers bred so-called 'knockout' mice that lacked the Dicer enzyme in adipose tissue specifically. These adipose-tissue-specific Dicer knockout (ADicerKO) mice did not produce the usual complement of miRNAs found in normal mice, showing that adipose tissue is responsible for making a large number of the circulating miRNAs. And this is important, because the presence of such miRNAs is associated with improvements in glucose tolerance and other beneficial metabolic changes. Indeed, the ADicerKO mice exhibited a decrease in brown adipose tissue (the most metabolically active type), as well as an increase in insulin resistance. However, when both brown and white adipose tissue from normal mice was transplanted into the knockout mice, they began to produce the miRNAs, demonstrating the importance of the adipose tissue in circulating miRNA production. In addition to their work with the mice, the investigators also compared miRNAs from patients with lipodystrophy [1] with those from control people. They found that the patients with lipodystrophy had lower levels of over 200 different miRNAs compared to the controls. Thus, both the animal and human data suggest an important role for adipose tissue in the regulation of metabolism, and may indicate an important avenue for future research into the roles of Dicer and miRNAs in the obesity-linked derangement of blood pressure, blood glucose regulation and insulin resistance. http://acsh.org/news/2017/03/02/when-fat-speaks-body-listens-10911
  2. 1 point
    Hope all is well with you AB2B. Been thinking of you Sent from my iPhone using the BariatricPal App
  3. 1 point
    mylighthouse

    Will I Ever Eat Spicy Again?

    Hi, I'm almost 16 weeks post op and I have loved spicy foods for my entire life too.... until now. I still love the taste, but can't tolerate onions, jalapenos or Sriracha anymore. I used to go through a bottle of Sriracha in a matter of a couple weeks. Every now and then I will try a little Sriracha to see if I am able to handle it.... but not yet. I really hope that I will be able to enjoy spicy food again someday.
  4. 1 point
    Good luck to you all. I'm 9 days post op. [emoji2]
  5. 1 point
    jjsasha

    Plastic Surgery Before Goal

    If it's bothering you and possibly hindering further weight loss I would absolutely have it removed.
  6. 1 point
    Jess55

    Surgery Monday 3/6

    I'm on the 6th too. Revising from the band. I had multiple last meals [emoji20]. I sadly gained weight from my last visit. But I'm on day 4 of my 7 day liquid diet. I've been wanting to revise for two years. I've unfortunately gained back all my weight plus a little due to band failure. I hope things go very well for all. Now that it's 4 days away I'm starting to get a little nervous. I'm hoping I have an easy recovery. Honestly I'm not worried to much about the pain, although last time day 1 sucked, but I was off pain meds by day 3. I'm worried about having trouble getting all me fluids in. I currently drink a lot of wyler's light (similar to crystal light).
  7. 1 point
    Gail Engebretson

    Terrified of gaining

    First of all - Congratulations on the weight loss - to all of you. I know how hard you've been working and what determination you have. I also know really really well the fear you are facing. I was in the same place 12 years ago. My surgery was 13 years ago this month. I lost 170 lbs and have managed to keep it off - Yeah! I was really afraid of re-gain those first couple of years - especially as my appetite came back. I've roller coastered a bit at times but have managed to stay within about a 15 lb range. Don't let the fear stress you out because that can act as a push into old eating habits. Here's a few things I did to help me stay stable. I changed my eating habits drastically in that first year while I could. I cut out all sugar, went low on the grains, stopped all fast food with the rare exception, and went organic. It was easy to do that in the beginning when I was v. motivated because I kept thinking long term. I set up good solid exercise routines - doing things I liked like biking, dancing, swimming and walking. I continued to do those things because I liked them. I didn't get on the treadmill or exercise bike because I didn't like them and knew I wouldn't keep it up. I also set up and have continued to do a simple weight training routine. I got help when I needed it - used the professionals in my program but also went outside for psychotherapy and life coaching. Lastly I worked hard at not freaking out when I did gain a pound or 2 or even 10! I'd just do an inventory of where I was getting slack - esp. with the rules of the pouch - and trusted myself to get back on track, even if it took me a few days or even a week. I didn't freak out, go into despair and start that downward spiral of beat myself up, eat more, beat myself up more, eat more, etc. This is all simply put here but I put in a lot of work and time and continued vigilance yet learning to let go and enjoy life up to this day. I know I'll never gain back that weight. Good luck to all of you. The fact that you are concerned and looking long term is a great sign that you'll make it!
  8. 1 point
    I am feeling the same right now. I am scheduled for tomorrow morning. I believe this feeling is completely normal. I can't wait to share my experience with you all.
  9. 1 point
    Thanks. I'll try to calm down.
  10. 1 point
    macmanjimmy

    Am I finished losing weight?

    HW: 585 SW: 499 CW: 268 Age: 47 Height: 6'1 Total Loss: 317lbs Date of surgery: 4/6/2015 find myself not losing any more weight, not a pound, in fact I see my weight go up 1-2 pounds this week and eating the same.. Calorie intake: 1200 calories Burn about: 2000 calories Workout: Recumbent Bike: (3X) 15 minutes at 4-5MPH, maximum tension..... Nutritionist, stated I cannot lose anymore weight, I have no more fat to burn and any additional weight I will be losing will be muscle. Current weight, 268 and the nutritionist stated, I have about 20-25 pounds of excess skin making my true weight 243lbs what are your thoughts on this? I think I still have more weight to lose, any advise?

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