Hi. Im almost 6 months post op and have lost 77 pounds and feeling great. My question is I had bloodwork today and my liver enzymes and alkaline phosphate levels are high and so is my B12 levels. Has anyone else experienced this? Havent talked to the doctor yet.

it's common for liver enzymes to be high that first year or so out of surgery. Rapid weight loss is really hard on livers. Mine were really high the first year - then they went back down to normal sometime during year 2 (I was still losing weight during year 2 since I had over 200 lbs to lose)

how high is your B12? mine is always over 1000. It's met with a shrug at my clinic. Once it got over 2000, and the PA at my surgeon's office just said I should cut back a bit on my supplement. He didn't seem alarmed by it at all. I know several people who say they feel better when their B12 is around 1000 or higher.

Thank you for easing my mind. My B12 was 1300. I see my surgeon on Jan. 4th for my 6 month check up. My alkaline phosphate was like 280. Thanks and congrats on your weight loss.

glad to see this posted, same thing with me, I'm 7 months post op.

My B12 is always high because I take a B12 supplement, and the doctor is not concerned about it. Don’t be too worried about your labs being outside of “normal” values because those values are generic, and as a bariatric patient, your results might be different from what the lab considers “normal” and still be fine. Your surgeon is an expert on bariatric patients and can review the results to see if there’s any reason for concern. I have also noticed that different laboratories have slightly different “normal” ranges for some things, so even then, if your results are slightly outside of what one place considers normal, they could be within the normal range of another place.

13 hours ago, db1955 said:

Thank you for easing my mind. My B12 was 1300. I see my surgeon on Jan. 4th for my 6 month check up. My alkaline phosphate was like 280. Thanks and congrats on your weight loss.

I just checked MyChart for my liver enzyme levels from a few years ago (I had surgery in 2015) - I had my liver enzymes checked a couple of times until they stabilized. My alkaline Phospate level was normal, but my ALT and AST (also liver enzymes) were way out of range (again, they stabilized at a normal level during year 2, once my rate of weight loss had slowed down to a crawl). But see what your surgeon says. It may be perfectly normal for the alkaline phosphate level to be way out of whack during the weight loss phase, too. I Just know it's pretty common to have crazy high liver enzyme levels that first year out of surgery.

Same for me. My B12 was high in the past, and my surgeon told me to switch to even one time per week, as my body might be absorbing more than I realize from meat.

On 12/28/2022 at 10:00 AM, catwoman7 said:

I just checked MyChart for my liver enzyme levels from a few years ago (I had surgery in 2015) - I had my liver enzymes checked a couple of times until they stabilized. My alkaline Phospate level was normal, but my ALT and AST (also liver enzymes) were way out of range (again, they stabilized at a normal level during year 2, once my rate of weight loss had slowed down to a crawl). But see what your surgeon says. It may be perfectly normal for the alkaline phosphate level to be way out of whack during the weight loss phase, too. I Just know it's pretty common to have crazy high liver enzyme levels that first year out of surgery.

I just got back my blood test and everything was good but my AST was almost out of range and my ALT was out of range at 35. I noticed it climbing every blood test. I'm at 1 year 7 months after my RNY revision. I was so concerned so I did a search here and found this. Thank you. I don't drink or do any of those "don't do this or it'll hurt you liver" things, even the diet no nos are not foods that I normally like, so I wasn't sure what is causing this. I have a check up with my bariatric team in a couple weeks but seeing this calmed me. Thanks again!