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I have had two fills now (4/11 & yesterday). I had a very hard time with the first one which was under fluro because it was the first. Apparently my port is tilted so that it is very hard to align the needle up with the hole in port (bull's eye). After several sticks, they were able to get it. The nurse practitioner tried to do the second one in the office last week but couldn't so i was scheduled to do it under fluro again yesterday. Still the same problems with not being able to see the bullseye. Then she thought that the port may be totally flipped. She said that sometimes as you lose weight, the fat and your insides shift so can cause port to tilt or even flip. So she took pictures and showed to the surgeon and another person to get a second opinion. The consensus was that my port was not filipped but at a very awkward position. She said that it is not anyone's fault and that sometimes it happens. She anticipates that it will get better as I lose more weight. I certainly hope so because I don't want to be the problem child and hate to get future fills or they hate to see me coming because I am "difficult". They were nice and all but i know it is frustrating for them as well as me. Then my blood sugar dropped from all of the sticks and stress so i had to lie down for awhile. They finally got it yesterday. I was a happy camper. I'm a little sore today from all the sticks but was worth it to me. Not trying to scare anyone, just sharing my experience. Just goes to show you that anything can happen and that it is indeed a journey. I have lost 40 pounds and alot of inches since January 19 and i have no regrets.