I was sleeved in April,& have lost over 90lbs. 2 years ago I was diagnosed with ADD & started vyvanse. I went off the med a few month later, because I didn't think I really needed it.

I started back on vyvanse a few weeks ago. I feel like it doesn't work the same way it did before surgery.

Do any of you feel like medication effects you differently since surgery? Do we absorb medication differently with our new stomach's?

I'm thinking my dose is just too high.

Suggestions please. Thanks!!

I'm still pre-op, so I don't know the answer, but I am wondering if it could also be that you have lost so much weight that the dosage is just more potent for your new weight. I also just want to see what others say because I may have a similar situation post-op.

You really need to talk to your doctor/pharmacist about this. People on a forum, although they've got loads of experience with VSG, cannot give you information about your drug dosage. The dosage can depend on a bunch of different factors, specific to you.

You really need to talk to your doctor/pharmacist about this. People on a forum' date=' although they've got loads of experience with VSG, cannot give you information about your drug dosage. The dosage can depend on a bunch of different factors, specific to you.[/quote']

I am not asking for advice on HOW to take my meds from others on here. I am asking if others have had this same experience. Theres a huge difference.

Vyvanse as with most add meds does not use a weight based dosage system so weight loss should not be the factor. I did find this article(http://www.medicine.virginia.edu/clinical/departments/medicine/divisions/digestive-health/nutrition-support-team/nutrition-articles/Chan_Part2_Article.pdf) discussing the effect of wls on medication absorption which seems to indicate that some meds are absorbed slower after wls which might account for the change in how the med is working for you since these meds are normally time released anyhow. Hope this is helpful and good luck.

Also keep in mind that some meds begin to be "broken down"in the stomach acid and with a sleeve, especially if on a PPI (protonix, Prilosec), this can vary a lot. Also, the transit time through the stomach is now different-just ideas why the same dose may be affecting you differently.

I actually had this conversation today.

I take a 1000 mg of metformin

I had my surgery on the 19th and was so nauseated that I was unable to take my meds day after surgery.

Anyway yesterday I started back and afterwards I felt really bad and almost zombie like.

So I called the pharmacist and she said most definitely I needed half that dose.

1.) some meds crushed absorb differently

2.) our diets have changed which could make our meds change.

I took a half day and felt soooo much better.

Also I remember during my pysch evaluation he told me some of my meds would most likely change.

Im No doctor... But I take tyroid, metformin, OCD, cholesterol and Birth control meds.

And I was told that all would prolly change except tyroid.

Not sure if anyone is following this, but I have a general warning for all post-GB patients who end up taking the pain/addiction treatment medication called, SUBOXONE:

Eventhough SUBOXONE is taken sublingually (under the tongue) 1 of it's 2 active ingredients, NALOXONE, is NOT absorbed under the tongue, it is actually swallowed and processed through the GI tract.

The average person has no negative side effects from NALOXONE b/c it is ultimately "destroyed" in their normal GI tract. However, in GB patients, it can cause extreme NEGATVE side effects!!

I am a post-GB patient who has taken, and suffered through SE's from, Suboxone for the past 4 years. I only recently became aware of the Naloxone absorption issue & feel compelled to share it w/others out there who may be suffering.

Bottom line: Post-Gastric Bypass patients should take SUBUTEX (BUPRENORPHINE) in place of SUBOXONE!!!!