Weight Loss Advice 'ignores Body Changes'
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http://www.nhs.uk/news/2012/02February/pages/metabolism-changes-during-weight-loss-diets.aspx
A number of interesting facts in this article including a link for a weight simulator that allows people to calculate how many calories you need to cut from your diet to get to target.
Interestingly, A clinical trial comparing low fat and low carb diets is recruiting in the US. I wish I could join but I don't live there. the link is in the article if you are interested.