I have had genetic testing, which does not show any predispotition to cancer, however there is no guarantee (nice double talk by the doctors). However, due to my obesity and the fact that my mother had a colonoscopy less than 6 mos to the cancer being detected with NO polyps or signs of abnormalities, basically given a clean bill of health, every 2 yrs is within reason for my pre-screening. And in relation, the prep is nothing compared to chemo. I am sure once I get my BMI within normal range I can go to every 5 yrs, at least this is the plan.