The Link Between Depression & Obesity
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Earlier this year an intriguing new study provided all of us working in industry with some invaluable insights into the link between depression and obesity.
Conducted by Dr Aurelie M Lasserre of Lausanne University Hospital in Switzerland, the study revealed that the atypical subtype of major depressive disorder is linked to greater risk of obesity; a link that’s not found in other subtypes of the illness.
The Study
The study was a prospective population-based cohort study that included 3,000 randomly selected Lausanne residents with a mean age of 50 years-old (53% women).
At baseline, 7.5% of the 3,000 participants met the criteria for MDD, with 37% having had a previous major depressive episode. Of these, about 10% experienced atypical depression and melancholic episodes, while 14% experienced purely atypical episodes.
The Findings
Dr Aurelie M Lasserre and her team found that the subjects who experienced atypical episodes of MDD tended to have a higher increase in adiposity [fat] than those with MDD, and were nearly four times more likely to be obese.
"For the clinician, the atypical subtype deserves particular attention, because this subtype is a strong predictor of adiposity," reported Dr. Lasserre. "Accordingly, the screening of atypical features and, in particular, increased appetite in individuals with depression is crucial."
The report, published in JAMA Psychiatry came to the conclusion that atypical MDD is a strong predicator of obesity, while those with melancholic, combined, or unspecified major depressive disorder (MDD) showed no greater risk for fat-mass gain than those without any form of MDD. The researchers found no evidence for medication or physical activity affecting the link between adiposity and atypical MDD.
“This study emphasises the need to identify individuals with this subtype of MDD in both clinical and research settings,” wrote Dr. Lasserre. “Therapeutic measures to diminish the consequences of increased appetite during depressive episodes with atypical features are strongly advocated.”