We should all know that with gastric bypass surgery NSAIDS can NEVER be taken again as they can cause bleeding ulcers. Additionally, during my pre-op education I didn’t understand the ramifications of time released medication and potential dosage absorption issues. (These facts were disclosed but until I was effected, I didn’t get it.) After surgery it took forever for my time-released medication to kick in and I had issues with two other medications. I was able to switch to a similar medication that isn’t time-released with the option for a second daily dose. As for the other medications that lost their full effectiveness or I could not tolerate due to nausea, my dosages were split from once per day to multiple smaller dosages throughout the day. I hope that this helps someone have a good discussion with their doctors and bypass surgeon.